This book provides students with the information and conceptual skills needed to transition from introductory to graduate-level organic chemistry and to fully comprehend published research. Chapters describe key aspects of organic synthesis stereochemistry, functional group transformations, bond formation, synthesis planning, mechanisms, and spectroscopy. It features extensive problems in each chapter for students to work through in learning the material. The new edition thoroughly updates it predecessor with new examples and literature references and discussion of online resources (like Chemical Abstracts Service or CAS) that are commonplace now for literature searches. An appendix on protecting groups has been added and a section on green chemistry added to the physical influences on reactions chapter. There is also a rewritten last chapter that surveys organic spectroscopy. An answer key with solutions to the chapter problems and Powerpoint slides for each chapter are available for adopting professors.