The Drug Discovery Handbook gives the professional a tool to facilitate drug discovery by bringing together, in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. The Handbook presents a comprehensive, practical guide for professionals involved in drug discovery. This practical guide will present an explanation of the latest techniques and methods in drug discovery, including: genomics, proteomics, high throughput screening, and systems biology. This resource summarizes how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, etc. Individual chapters detail specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques. This background provides the professional with understanding and guidance for approaching new problems. The approaches and methodologies presented in the Handbook will provide a practical problem solving approach that is scientifically valid and aids readers in the task of developing new drugs.