This textbook is the first comprehensive approach to combine, in a unified way, the three fields of Systems Engineering, Operations, and multi criteria decision-making (MCDM). All traditional application problems in System Engineering and Operations Systems are formulated and solved using unique MCDM approaches. The emphasis of this book is on: How Systems are designed? How Systems are engineered? How to model and solve each well-known application problems? How to solve problems with multiple and conflicting objective? How to formulate operations, productions, and manufacturing systems problems and solvethem? For each problem example, a sample spreadsheet is also provided to make the use of methods easy for all students and practitioners. The authors include several robust methods for solving MCDM and MOO problems. This book also introduces several completely new chapters and sections not covered in any other text books. They include chapters in Small-Scale Design such as Cellular Layouts and Networks, MCDM of all problems, models, and methods, and New MCDM and MOO methods for solving problems.