This book ties reaction mechanisms, synthetic methodology, and biological applications together to form an integrated picture of advanced organic chemistry. It is a concept-based, practical textbook, presenting synthetic and biological perspectives about organic reaction mechanisms. The book offers a useful guide for how to analyze, understand, approach, and solve the problems of organic reactions with the help of mechanistic studies. Most recent significant findings in organic reaction mechanisms are covered by good referencing to important journal articles. Including end-of-chapter problems and separate solutions manual, the book serves as a student-friendly textbook in advanced organic chemistry as well as a resource for practicing chemists.