This EMR Book provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers. Recent developments in pulse sequences for ssNMR studies have allowed a wonderful range of biological systems to be studied in atomic detail. While the field is still growing apace, the collection of pulse sequences has reached a point that an overview and discussion surely warranted. The central core of the volume is an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. This is supplemented with practical examples of biochemical applications, and detailed discussion of the many aspects of sample preparation and handling that make spectrocopy on solid proteins successful.  The structure, conformational dynamics, and the binding of various factors to biopolymers can be probed by Solid State NMR, as has been very recently demonstrated in a number of laboratories. Numerous advances in technology have led to this rapid growth in the field, and the recent developments in pulse sequences has been particularly crucial for developing these capabilities. The popular nature of this topic is principally due to the range of biomedical problems that can be addressed with ssNMR; without need for crystals or monodispersed pure solutions, this method can study quite complex systems, which provides the possibility of very functionally relevant states and very large complexes.